- Drive or support target identifications in collaboration with translational medicine, disease biology research, and chemistry teams.
- Initiate new drug discovery projects based on scientific insight with cross-functional input.
- Design and implement various in vitro and in vivo studies to study potency, selectivity, and to elucidate molecular mechanism of drug action and efficacy based on scientific considerations within the context of team or project goals.
- Perform scientific analysis for results interpretation and present them collaboratively.
- Initiate and execute research activities related to identification and characterization of novel therapeutic targets and compounds.
- Investigate and develop methods or technologies for the rapid advancement of projects.
- Prepare standard operational protocols, study reports and high-quality manuscripts.
- Other related duties as required, including but not limiting to organizing and maintaining laboratory and training associates and/or junior scientists.
- Work in a flexible schedule to meet deadlines.
- Should communicate effectively, collaborate efficiently with co-workers (cross functions and/or sites), and be able to train junior level associates and/or scientists.
- Deep knowledge of immunology is required
- Disease biology of the gut, kidneys and connective tissues is preferred.
- Should be proficient in designing and conducting experiments involving the state of the art techniques within the areas of immunology, biochemistry, molecular biology, and pharmacology.
- Be capable of understanding chemistry and DMPK results and collaborating effectively cross functions.
- Recognize novelty of patentable ideas where applicable and contribute to patents.
- Contribute to scientific publications.
- Good communication in English and be capable of presenting results both inside and outside of company.
- Have and maintain thorough knowledge of related scientific field and apply this knowledge to advance projects or programs.
- Be able to record and present results in English, fluent Chinese is a plus.
- Title of positions (Principal Associate, Scientist, and Senior Scientist) matched with candidate's qualifications and years of experience.
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Scientist / Senior Scientist / Principal Scientist, Immunology Discovery - Shanghai, 中国 - Roche
描述
The Position
Primary Purpose of Job
Collaborate with a group of immunology scientists and associates to provide expert biology support to preclinical and clinical studies for the discovery and development of new therapeutic agents. Scientists are responsible for contributing to new medical hypothesis, new target validation, new project initiation and progression, and drafting and execution of research plans for nominating new projects. Commensurate with experience, scientists expected to lead cross-functional discovery project team(s) and/or support projects with biology expertise. Apply skills in drug discovery to assess the potency, selectivity, safety, PK and PD of novel molecules. Strong background in immunology and experience with autoimmune diseases or kidney diseases preferred.
Principle Roles & Responsibilities / Accountabilities
Qualification and in immunology, nephrology, rheumatology or a related field. PhD with medical knowledge (MD) is a plus. Post-doctoral training experience is preferred. Industrial experience in drug discovery is a plus. Oversea education and/or training experience is preferred.
Leadership Competencies
Job Required Competencies
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