小核酸药物纯化与分析高级研究员 - Shanghai

仅限注册会员 Shanghai, 中国

2周前

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该职位来源于猎聘 岗位定位 核心技术岗,聚焦小核酸药物(siRNA/ASO等)早期研发阶段的分析方法与纯化工艺开发、优化及落地,对早研样品质量控制和专项技术可行性负责,支撑项目早期筛选到IND申报前的核心技术工作。 核心职责 · 1. 纯化工艺开发与平台建设(主导) · 负责小核酸药物纯化工艺开发、优化与平台搭建,主导建立基于制备型液相色谱(RP-HPLC, IEC, HIC)和膜分离的核心纯化策略。 · 攻克复杂样品(长链、修饰、双靶点siRNA、GalNAc/抗体偶联物等)的分离纯化挑战,针对性解决有关物质去除与收率提升等关键问题。 · 结合早研阶段 ...
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