BeiGene B

Senior Principal Investigator/Associate Director in DMPK (BB-C51DD)

Found in: Expertini China

BeiGene continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer. Job Description: The DMPK Department of BeiGene is seeking a highly motivated individual to lead the large molecule ADME group at its newly established Shanghai Research Center. The successful candidate must have in depth knowledge of quantitative measurement or qualitative understanding of large molecules using ELISA or orbitrap, in vivo biotransformation of large molecules, design hypothesis driven studies to solve issues pertaining to ADME of large molecules. Job description: Function as a project leader in a multidisciplinary collaborative environment with primary responsibility for the early preclinical development of antibodies and/or ADC; Integrate pharmacokinetics and PK/PD with discovery biology, in vivo pharmacology to define structure activity relationships guiding protein engineering strategies and optimization of protein therapeutics; Interact across interdisciplinary teams, including biology, discovery research, protein engineering, regulatory agencies, and functional groups within drug disposition; Lead preparation of relevant sections of regulatory documents for development and registration of new drugs and line extensions; interact with regulatory agencies worldwide; Foster relationships through coaching and mentorship of fellow scientists; Oversight of study design and execution for non-clinical PK and PK/PD studies, TK studies; Excellent written and verbal communication of scientific data, both internally and in the scientific community. Qualification Required: Requirements: Ph.D. in Biochemistry/Biology/Cell Biology/Pharmacokinetics or a related scientific field; Experience in the development of biologics such as monoclonal antibodies, ADC or bispecific Ab. Follow Us on MoSeeker!

calendar_today1 month ago

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info Full time

location_onShanghai, China

work BeiGene

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